Gene information
Official symbol MIR146A
Official full name microRNA 146a
Gene type microRNA
Chromosome5q33.3
Alias symbolhsa-mir-146; hsa-mir-146a
Previous symbolMIRN146; MIRN146A
Gene familyMicroRNA MIR146 family
Resources
Entrez Gene 406938
HGNC HGNC:31533
Ensembl ENSG00000283733
UCSC uc021yhe.1
GO terms: 158 records
GO Description Category LogP Number of genes Detail
GO:0001666 response to hypoxia GO Biological Processes -40.6131384 77 More
GO:0001678 cellular glucose homeostasis GO Biological Processes -13.5994972 27 More
GO:0001818 negative regulation of cytokine production GO Biological Processes -48.9957481 97 More
GO:0001933 negative regulation of protein phosphorylation GO Biological Processes -19.8214973 59 More
GO:0001936 regulation of endothelial cell proliferation GO Biological Processes -54.5504306 75 More
GO:0001937 negative regulation of endothelial cell proliferation GO Biological Processes -27.2173755 21 More
GO:0001938 positive regulation of endothelial cell proliferation GO Biological Processes -32.0012114 45 More
GO:0002237 response to molecule of bacterial origin GO Biological Processes -48.4964960 93 More
GO:0002683 negative regulation of immune system process GO Biological Processes -26.6415063 77 More
GO:0002686 negative regulation of leukocyte migration GO Biological Processes -7.70467721 14 More
GO:0003729 mRNA binding GO Molecular Functions -83.3296105 82 More
GO:0003730 mRNA 3'-UTR binding GO Molecular Functions -66.9774057 54 More
GO:0006417 regulation of translation GO Biological Processes -24.5257987 35 More
GO:0007162 negative regulation of cell adhesion GO Biological Processes -21.5212108 58 More
GO:0008285 negative regulation of cell population proliferation GO Biological Processes -53.5569125 147 More
GO:0009615 response to virus GO Biological Processes -11.2861143 47 More
GO:0009743 response to carbohydrate GO Biological Processes -20.6536066 44 More
GO:0009746 response to hexose GO Biological Processes -16.2230361 35 More
GO:0009749 response to glucose GO Biological Processes -15.7538948 34 More
GO:0009895 negative regulation of catabolic process GO Biological Processes -10.3621088 43 More
GO:0010563 negative regulation of phosphorus metabolic process GO Biological Processes -21.7837721 71 More
GO:0010574 regulation of vascular endothelial growth factor production GO Biological Processes -24.2705452 18 More
GO:0010594 regulation of endothelial cell migration GO Biological Processes -41.8778170 72 More
GO:0010595 positive regulation of endothelial cell migration GO Biological Processes -28.3201829 45 More
GO:0010596 negative regulation of endothelial cell migration GO Biological Processes -31.4991544 25 More
GO:0010632 regulation of epithelial cell migration GO Biological Processes -42.8870194 81 More
GO:0010633 negative regulation of epithelial cell migration GO Biological Processes -29.7632977 25 More
GO:0010634 positive regulation of epithelial cell migration GO Biological Processes -29.2566722 52 More
GO:0010721 negative regulation of cell development GO Biological Processes -6.74707916 25 More
GO:0010942 positive regulation of cell death GO Biological Processes -48.7037743 123 More
GO:0014013 regulation of gliogenesis GO Biological Processes -13.3514185 26 More
GO:0016441 post-transcriptional gene silencing GO Biological Processes -100 124 More
GO:0016525 negative regulation of angiogenesis GO Biological Processes -31.9326641 51 More
GO:0017148 negative regulation of translation GO Biological Processes -31.7864246 33 More
GO:0019725 cellular homeostasis GO Biological Processes -21.1508273 85 More
GO:0022408 negative regulation of cell-cell adhesion GO Biological Processes -15.9068791 40 More
GO:0030155 regulation of cell adhesion GO Biological Processes -41.8400792 131 More
GO:0030335 positive regulation of cell migration GO Biological Processes -66.7331035 139 More
GO:0030336 negative regulation of cell migration GO Biological Processes -30.9008082 37 More
GO:0030371 translation repressor activity GO Molecular Functions -100 82 More
GO:0031047 gene silencing by RNA GO Biological Processes -100 125 More
GO:0031330 negative regulation of cellular catabolic process GO Biological Processes -6.88355184 32 More
GO:0031347 regulation of defense response GO Biological Processes -64.5971043 148 More
GO:0031348 negative regulation of defense response GO Biological Processes -30.3795513 65 More
GO:0031400 negative regulation of protein modification process GO Biological Processes -17.0986645 70 More
GO:0032102 negative regulation of response to external stimulus GO Biological Processes -54.2675416 110 More
GO:0032496 response to lipopolysaccharide GO Biological Processes -45.257773 87 More
GO:0032642 regulation of chemokine production GO Biological Processes -25.2850711 37 More
GO:0032675 regulation of interleukin-6 production GO Biological Processes -28.2553997 51 More
GO:0032677 regulation of interleukin-8 production GO Biological Processes -20.0046302 33 More
GO:0032682 negative regulation of chemokine production GO Biological Processes -6.18749803 9 More
GO:0032715 negative regulation of interleukin-6 production GO Biological Processes -14.4703936 13 More
GO:0032717 negative regulation of interleukin-8 production GO Biological Processes -6.55714834 6 More
GO:0033500 carbohydrate homeostasis GO Biological Processes -23.7918768 50 More
GO:0034121 regulation of toll-like receptor signaling pathway GO Biological Processes -7.06389205 16 More
GO:0034122 negative regulation of toll-like receptor signaling pathway GO Biological Processes -3.57905448 8 More
GO:0034248 regulation of cellular amide metabolic process GO Biological Processes -28.1662419 40 More
GO:0034249 negative regulation of cellular amide metabolic process GO Biological Processes -35.7644618 37 More
GO:0034284 response to monosaccharide GO Biological Processes -18.9205843 39 More
GO:0035194 post-transcriptional gene silencing by RNA GO Biological Processes -100 124 More
GO:0035195 miRNA-mediated gene silencing GO Biological Processes -100 124 More
GO:0035278 miRNA-mediated gene silencing by inhibition of translation GO Biological Processes -46.1099674 32 More
GO:0036293 response to decreased oxygen levels GO Biological Processes -40.9544531 79 More
GO:0036294 cellular response to decreased oxygen levels GO Biological Processes -14.5279047 32 More
GO:0038061 NIK/NF-kappaB signaling GO Biological Processes -4.66781085 9 More
GO:0040013 negative regulation of locomotion GO Biological Processes -30.7871461 81 More
GO:0040017 positive regulation of locomotion GO Biological Processes -69.9490345 147 More
GO:0040036 regulation of fibroblast growth factor receptor signaling pathway GO Biological Processes -4.66781085 9 More
GO:0042326 negative regulation of phosphorylation GO Biological Processes -20.6187298 64 More
GO:0042593 glucose homeostasis GO Biological Processes -23.8963802 50 More
GO:0043065 positive regulation of apoptotic process GO Biological Processes -46.1285536 112 More
GO:0043068 positive regulation of programmed cell death GO Biological Processes -46.5713594 114 More
GO:0043535 regulation of blood vessel endothelial cell migration GO Biological Processes -45.8916712 37 More
GO:0043536 positive regulation of blood vessel endothelial cell migration GO Biological Processes -25.0316183 33 More
GO:0043537 negative regulation of blood vessel endothelial cell migration GO Biological Processes -32.3610392 24 More
GO:0045182 translation regulator activity GO Molecular Functions -97.0300828 82 More
GO:0045596 negative regulation of cell differentiation GO Biological Processes -26.9785067 101 More
GO:0045765 regulation of angiogenesis GO Biological Processes -63.6171248 109 More
GO:0045936 negative regulation of phosphate metabolic process GO Biological Processes -21.8424865 71 More
GO:0046425 regulation of receptor signaling pathway via JAK-STAT GO Biological Processes -10.5317026 20 More
GO:0050678 regulation of epithelial cell proliferation GO Biological Processes -51.9930445 102 More
GO:0050679 positive regulation of epithelial cell proliferation GO Biological Processes -31.4834672 59 More
GO:0050680 negative regulation of epithelial cell proliferation GO Biological Processes -26.5961536 48 More
GO:0050708 regulation of protein secretion GO Biological Processes -30.3716714 63 More
GO:0050709 negative regulation of protein secretion GO Biological Processes -12.5236372 21 More
GO:0050727 regulation of inflammatory response GO Biological Processes -68.5964592 121 More
GO:0050728 negative regulation of inflammatory response GO Biological Processes -31.0556128 55 More
GO:0050730 regulation of peptidyl-tyrosine phosphorylation GO Biological Processes -27.1120967 60 More
GO:0050767 regulation of neurogenesis GO Biological Processes -15.7439029 55 More
GO:0051046 regulation of secretion GO Biological Processes -54.0079540 130 More
GO:0051048 negative regulation of secretion GO Biological Processes -20.2278199 42 More
GO:0051051 negative regulation of transport GO Biological Processes -46.8709407 107 More
GO:0051052 regulation of DNA metabolic process GO Biological Processes -4.01973325 42 More
GO:0051223 regulation of protein transport GO Biological Processes -25.2801266 81 More
GO:0051224 negative regulation of protein transport GO Biological Processes -11.0190941 26 More
GO:0051271 negative regulation of cellular component movement GO Biological Processes -29.9238399 37 More
GO:0051272 positive regulation of cellular component movement GO Biological Processes -66.5150412 143 More
GO:0051896 regulation of protein kinase B signaling GO Biological Processes -30.5149255 55 More
GO:0051898 negative regulation of protein kinase B signaling GO Biological Processes -8.06132628 15 More
GO:0051960 regulation of nervous system development GO Biological Processes -17.2202851 64 More
GO:0055082 cellular chemical homeostasis GO Biological Processes -17.6289728 71 More
GO:0060251 regulation of glial cell proliferation GO Biological Processes -8.90876897 12 More
GO:0060284 regulation of cell development GO Biological Processes -22.9455891 78 More
GO:0060353 regulation of cell adhesion molecule production GO Biological Processes -7.13135320 9 More
GO:0060354 negative regulation of cell adhesion molecule production GO Biological Processes -5.49388035 4 More
GO:0062207 regulation of pattern recognition receptor signaling pathway GO Biological Processes -5.69211704 17 More
GO:0070201 regulation of establishment of protein localization GO Biological Processes -24.4831554 82 More
GO:0070482 response to oxygen levels GO Biological Processes -40.7566635 82 More
GO:0070555 response to interleukin-1 GO Biological Processes -18.9736890 36 More
GO:0071216 cellular response to biotic stimulus GO Biological Processes -28.1549742 59 More
GO:0071219 cellular response to molecule of bacterial origin GO Biological Processes -28.3848077 56 More
GO:0071222 cellular response to lipopolysaccharide GO Biological Processes -26.0381191 52 More
GO:0071322 cellular response to carbohydrate stimulus GO Biological Processes -12.8816523 25 More
GO:0071326 cellular response to monosaccharide stimulus GO Biological Processes -13.2453179 24 More
GO:0071331 cellular response to hexose stimulus GO Biological Processes -12.5306046 23 More
GO:0071333 cellular response to glucose stimulus GO Biological Processes -12.7795214 23 More
GO:0071396 cellular response to lipid GO Biological Processes -37.0669488 98 More
GO:0071417 cellular response to organonitrogen compound GO Biological Processes -26.3253267 90 More
GO:0071453 cellular response to oxygen levels GO Biological Processes -14.8173809 34 More
GO:0071456 cellular response to hypoxia GO Biological Processes -14.4449186 31 More
GO:0090049 regulation of cell migration involved in sprouting angiogenesis GO Biological Processes -34.2220297 25 More
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis GO Biological Processes -13.3704113 10 More
GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis GO Biological Processes -23.4562080 16 More
GO:0090287 regulation of cellular response to growth factor stimulus GO Biological Processes -21.1381780 60 More
GO:0090559 regulation of membrane permeability GO Biological Processes -4.72352826 6 More
GO:0098586 cellular response to virus GO Biological Processes -6.52248641 17 More
GO:1900015 regulation of cytokine production involved in inflammatory response GO Biological Processes -18.8349263 16 More
GO:1900016 negative regulation of cytokine production involved in inflammatory response GO Biological Processes -7.97228906 7 More
GO:1901222 regulation of NIK/NF-kappaB signaling GO Biological Processes -7.00394995 9 More
GO:1901223 negative regulation of NIK/NF-kappaB signaling GO Biological Processes -6.41916919 6 More
GO:1901342 regulation of vasculature development GO Biological Processes -64.8504074 111 More
GO:1901343 negative regulation of vasculature development GO Biological Processes -32.5354692 52 More
GO:1901652 response to peptide GO Biological Processes -34.9047734 89 More
GO:1901699 cellular response to nitrogen compound GO Biological Processes -26.9091664 96 More
GO:1902532 negative regulation of intracellular signal transduction GO Biological Processes -29.4927428 92 More
GO:1903037 regulation of leukocyte cell-cell adhesion GO Biological Processes -23.2079690 66 More
GO:1903038 negative regulation of leukocyte cell-cell adhesion GO Biological Processes -10.2281373 27 More
GO:1903231 mRNA base-pairing post-transcriptional repressor activity GO Molecular Functions -100 82 More
GO:1903530 regulation of secretion by cell GO Biological Processes -45.6472055 114 More
GO:1903531 negative regulation of secretion by cell GO Biological Processes -17.4034654 36 More
GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis GO Biological Processes -28.1722563 19 More
GO:1903589 positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis GO Biological Processes -13.7390860 9 More
GO:1903828 negative regulation of protein localization GO Biological Processes -8.86943289 30 More
GO:1904046 negative regulation of vascular endothelial growth factor production GO Biological Processes -20.8132034 13 More
GO:1904464 regulation of matrix metallopeptidase secretion GO Biological Processes -13.0040256 7 More
GO:1904892 regulation of receptor signaling pathway via STAT GO Biological Processes -12.9980471 24 More
GO:1904893 negative regulation of receptor signaling pathway via STAT GO Biological Processes -5.45308560 5 More
GO:1904950 negative regulation of establishment of protein localization GO Biological Processes -11.4813166 27 More
GO:1904994 regulation of leukocyte adhesion to vascular endothelial cell GO Biological Processes -9.55155535 14 More
GO:1904995 negative regulation of leukocyte adhesion to vascular endothelial cell GO Biological Processes -5.76984713 4 More
GO:1905952 regulation of lipid localization GO Biological Processes -40.6150331 64 More
GO:1905953 negative regulation of lipid localization GO Biological Processes -25.1573575 31 More
GO:2000112 regulation of cellular macromolecule biosynthetic process GO Biological Processes -24.0725356 37 More
GO:2000113 negative regulation of cellular macromolecule biosynthetic process GO Biological Processes -32.997895 35 More
GO:2000146 negative regulation of cell motility GO Biological Processes -30.256132 37 More
GO:2000147 positive regulation of cell motility GO Biological Processes -67.8620360 143 More
GO:2000181 negative regulation of blood vessel morphogenesis GO Biological Processes -32.6997315 52 More
GO:2000772 regulation of cellular senescence GO Biological Processes -3.74766542 9 More
KEGG pathways: 1 record
KEGG Description Category LogP Number of genes Detail
hsa05206 MicroRNAs in cancer KEGG Pathway -100 81 More
Related studies: 4 records
Molecular factor Omics type Application Objective MI type Reference
hsa-miR-146a-5p transcriptomics good predictor left ventricular remodeling[prognosis (bad)] acute ST elevation myocardial infarction Liu X et al. Cardiology. 2015
hsa-miR-146a-5p transcriptomics acute myocardial infarction[diagnosis] acute myocardial infarction Kazimierczyk E et al. Pharmacol Rep. 2019
hsa-miR-146a-5p transcriptomics excellent predictor acute myocardial infarction[diagnosis] acute myocardial infarction Xue S et al. Mol Med. 2019
hsa-miR-146a-5p transcriptomics good predictor acute ST elevation myocardial infarction[diagnosis] acute ST elevation myocardial infarction Bukauskas T et al. Med Sci Monit. 2019
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